But none of this can happen if we don't get enough sleep. Prolonged periods of sleep deprivation may have serious effects on our health, in addition to making us wake up the next day cranky and finding it difficult to focus. In fact, a lot of research has been done on what exactly happens to the various body parts when we don't get our recommended eight hours of sleep per night.
These studies have revealed that a lack of sleep can lead to a wide range of serious and life-threatening conditions, including diabetes, cancer, and heart problems. So what medical conditions are specifically associated with insufficient sleep?
1. Alzheimer’s
A 2013 study conducted by researchers at Johns Hopkins University found that a lack of sleep can both be a cause of Alzheimer’s disease and impact the speed of the disease’s progression. The study was conducted based on previous research that discovered sleep is necessary for the brain to get rid of “cerebral waste,” or the garbage-like buildup that can accumulate and cause dementia.
Conducting their study on 70 adults, ranging between the ages of 53 and 91, researchers found that those who reported getting poor sleep each night showed a greater amount of beta-amyloid deposition in their brains on PET scans. This compound is known to be a definitive marker of Alzheimer’s disease, leading researchers to conclude that lack of sleep is preventing the brain from getting rid of this form of “cerebral waste.”
Source: Spira AP, Gamaldo AA, An Y, et al. Self-reported Sleep and β-Amyloid Deposition in Community-Dwelling Older Adults. JAMA Neurology. 2013.
2. Obesity and Diabetes
Diabetes has long been linked to poor sleep, but a recent study conducted by researchers at the University of Chicago unpacked how poor sleep can potentially cause obesity, and ultimately, lead to diabetes. Knowing that fatty acid levels within the blood can impact metabolism speed and insulin’s ability to regulate blood sugar, researchers examined the effects little sleep had on fatty acid buildup.
Examining 19 men’s sleeping patterns, researchers found that those who got only four hours of sleep over the span of three nights had high levels of fatty acid within their blood between 4 a.m. and 9 a.m. This was a 15 to 30 percent increase over those who got 8.5 hours of sleep each night. Also, researchers found that the increase in fatty acid levels caused a higher degree of insulin resistance, all signs they attribute to pre-diabetes. Those who got more sleep, however, did not present the same markers for obesity or pre-diabetes.
3. Cardiovascular Disease
Cardiovascular disease has been linked to poor sleep for some time now, but a recent study presented at EuroHeartCare, the annual meeting of the European Society of Cardiology found greater evidence of a strong correlation. After following 657 Russian men between the ages of 25 and 64 for 14 years, researchers found that nearly two-thirds of those who experienced a heart attack also had a sleep disorder.
What’s more, the men that complained of sleep disorders also were found to have a 2.6 times higher risk of myocardial infraction, a heart attack that occurs when the heart muscle dies, and a 1.5 to four times greater risk of stroke.
4. Suicide
It may be shocking, but recent research conducted in 2014 found a link between increased incidences of suicide in adults and poor sleep, regardless of past history with depression. During a 10-yearstudy conducted by researchers at the Stanford University of Medicine, 420 participants ranging in middle to late adulthood were examined. Out of this group, 20 participants found to suffer from poor sleep unfortunately committed suicide. Because of this, researchers concluded that those who were experiencing difficulties sleeping on a consistent basis were 1.4 times more likely to commit suicide.
Those who were more vulnerable to this effect of poor sleep, researchers say, were white males 85 years or older. The study ultimately attributed this increased rate of suicide due to sleep deprivation associated with health problems and stress that increases with age.
5. Ulcerative colitis
Ulcerative colitis, an inflammatory bowel disease marked by ulcers within the lining of your digestive tract, as well as Crohn’s Disease can be a product of both sleep deprivation, and excess sleep, says a 2014 study. Researchers from Massachusetts General Hospital found that the right amount of sleep is necessary to curb inflammation responses within the digestive system which often lead to the two diseases.
After studying women enrolled within the Nurses’ Health Study (NHS) I since 1976 and NHS II since 1989, researchers found that risks of ulcerative colitis increased as sleep per night decreased to six hours or less. Alternately, researchers also found that more than nine hours of sleep increased risks as well, suggesting that the threshold for stopping digestive inflammation is a very narrow window that requires just the right amount of shut-eye. Although this response was only found within adult women, the increased chances of developing ulcerative colitis when getting little sleep existed despite other factors like age, weight, and habits like smoking and drinking.
6. Prostate Cancer
In a 2013 study published within the journal Cancer Epidemology, Biomarkers and Prevention, researchers found an increased incidence and severity of prostate cancer in patients with sleep issues. After following 2,425 Icelandic men between the ages of 67 and 96 for three to seven years, researchers discovered that the danger of developing prostate cancer rose in 60 percent of men who had trouble falling asleep. This number doubled with men who reported having difficulty staying asleep. What’s more, those who experienced sleep problems were also more likely to have later stages of prostate cancer.
Researchers of the study attribute this link to melatonin, a hormone known to regulate sleep. Higher levels of melatonin have been previously founded to suppress tumor growth, while levels of melatonin in those exposed to too much artificial light (a known cause of sleep deprivation) were found to have more aggressive tumor growth.