In America, the interest for professionally prescribed medications has soar in ongoing decades, with almost 70% of Americans on some sort of physician endorsed medication[1]. A great many people don't reconsider before popping the pill their specialist recommends – all things considered, it was affirmed by the FDA, and your specialist did got to restorative school, so it must be protected. Isn't that so?
Lamentably, as surfacing thinks about start investigating the FDA, its endorsement procedure, and the lifetime of the affirmed drugs, startling acknowledge are starting to show up. Indeed, over 30% of medications, showcased toward people in general with the FDA's blessing, are probably going to be engaged with a post-advertise wellbeing event[2]. These occasions are frequently genuine, involving 280,000 preventable hospitalizations each year[3], and notwithstanding ending the lives of a few patients. They've been seen in such a large number of various medications and the more genuine ones, similar to Vioxx, a NSAID that caused countless sudden heart assaults and passing, are in the long run removed the market.
Be that as it may, what happens when the FDA perceived genuine dangers related with medications and doesn't take them off the market?
Billions of individuals unconsciously open themselves to serious harm, and even demise. I trust one region this current nation's therapeutic industry truly needs is in the educated assent field. Numerous patients are actually never cautioned of the dangers, and I see this so frequently when chatting with other ladies about anti-conception medication
In this way, today, we will discuss five exceptionally regular medications that might cause such a great amount of damage to one precious organ: your mind.
1. Benadryl and Dementia
In 2010, the University of Indiana came forward with news that made headlines, and really made a number of people start questioning everyday mediations – including myself. A certain type of drug, anticholinergics, which can be found in medications like Benadryl and Tylenol PM, Unisom, Paxil, Phenergan, and so many more, have the ability to lead to an increased risk of cognitive decline, memory impairment, and non-Alzheimer’s dementia[4]. If I knew it then, I 100% am certain that I would’ve been rethinking all those Benadryl I’ve popped to simply help me get some sleep.
Another study, just conducted in 2017 and led by the Washington’s School of Pharmacy[5] came to the same conclusions they did, now eight years ago, the risk to the brain is very, very real. Comparative brain scans have actually revealed a lower metabolism and reduced brain size in people taking the drugs in question, and while being on them more long-term is associated with more risk, dosing for “the equivalent of three years or more was associated with a 54% higher dementia risk“, in the older population, just a few months’ exposure can be catastrophic[6, 7]. For those in the aging population, anticholinergic use proved to eventually lead to a 100% increased risk of cognitive decline[8].
2. Xanax and Brain Damage
Overprescription of and serious brain damage caused by another type of drug, benzodiazepines – found in common medications like Ativan, Xanax, Valium, and Klonopin – has been discussed and debated since the 1970s when they were first released. In 1975, Dr. Knott from the University of Tennessee waved a red flag, saying “I am very convinced that Valium, Librium and other drugs of that class cause damage to the brain. I have seen damage to the cerebral cortex that I believe is due to the use of these drugs, and I am beginning to wonder if the damage is permanent.”[13] Not only that, but correspondence between researchers and doctors in Britain’s Medical Research Council between 1981 and 1982 uncovered unsettling news for patients taking benzodiazepines, especially long-term. Not only was dependence a serious concern (benzodiazepine deaths have skyrocketed in recent years[9], but CAT scans of patients taking benzodiazepines were showing abnormal, harrowing results[10]. Of course, these findings would be buried and hidden away until finally being leaked to the public in 2010 through the media[11].
Between 1996 and 2013, benzodiazepine prescription increased nearly 70%[12] and a growing number of people became dependent on these medications, exposing themselves to an unforetold number of risks. Studies funded by the maker of the drug have disclosed side effects (that affected more than half the patients involved) that were either ignored or widely diminished, including sedation, ataxia (uncoordinated movement, usually resulting from neurological damage), fatigue, and even ventricular enlargement[14]. One of the scariest aspects of benzodiazepine use? It may be impossible to stop. Studies have concluded that after more than a few weeks of treatment, it is extremely difficult to discontinue benzodiazepine therapy, because of physical and psychological dependence[15].
3. Chemotherapy and Cognitive Damage
Commonly referred to by those in the medical industry, cancer survivors, and cancer families as “Chemo Brain”, the harmful effects of chemotherapy on the brain are pretty widely recognized. Toxic to healthy, non-cancer cells of the patient, chemotherapy makes a harsh attempt to try and destroy tumor cells, while also wreaking havoc on the entire body. And, while people who turn to chemotherapy think they’re facing a death sentence without it, chemotherapy is often successful less than 20% of the time. The American Medical Association says that there is no way to prevent or treat the condition, and that chemo brain symptoms often include a feeling of “brain fog”, difficulty with new learning, taking longer to complete tasks, trouble multitasking, and difficulty finding the right word[16]. Neurotoxic complications are often recognized by treating physicians, and this is one of the most common reasons for limiting the dosage of the therapy, as they tend to happen frequently. These complications range from mild cognitive deficits, like those explained by the JAMA Network, to widespread brain inflammation, aseptic meningitis, dementia, and coma[17].
4. Antidepressants and Neurological Damage
With the turn of the millennium, antidepressant use skyrocketed in the United States, and prescription rates increased nearly 400% between 1994 and 2008[18]. They were the third most commonly prescribed drug in those years, with women still being more likely to take them. Many of these drugs, like Zoloft and Prozac, have become household names – but most are not informed of the very real risks they carry, especially for the brain. The majority of patients take these drugs for more than two years, but evidence has surfaced revealing that brain architecture is altered mere hours after taking the first dose[19]. Scans taken three hours after the first dose of an SSRI antidepressant (like Lexapro or Paxil) showed reduced blood-oxygenation in certain structures of the brain, reduced functionality of the brain, and even neuronal damage. This damage even causes mature neurons to “revert back to an immature state”, and this can lead to developmental problems, romantic and sexual problems, and an increased risk of bleeding, stroke, and even death in certain populations. In fact, some researchers have even concluded that antidepressants generally do more harm than good[20].
In 2004, it was required of all antidepressant manufacturers, by the FDA, to include a black box warning on their package inserts “in order to call attention to an increased risk of suicidal thoughts and behavior” in certain populations taking their drugs[21]. The worst outcome to depression is obviously suicide, and the fact that antidepressants increase the likelihood of suicide and suicidal thoughts is extremely concerning. Unfortunately, that’s not all they do though. Antidepressants have not only been known to worsen the long-term course of depression[22,23], but they can also lead to other issues like mania and psychosis[24], and bipolar disorder[25].
5. Tylenol and ADHD
I don't generally shroud my solid perspectives on Tylenol, as I have done plenty of research to understand just how harmful it really is. Though it is most commonly recognized by its over-the-counter name, Tylenol, Acetaminophen is really the drug we’re going to be talking about – and it can be found in countless products, like Alka Seltzer, Nyquil, and Sudafed, and prescription medications like Tramadol, Lortab, and Oxycodone. There are approximately 28 billion doses of Acetaminophen sold per year in the US alone, and it is marketed to all populations, from the tiniest baby to the oldest person, to even women carrying an unborn child. But research is surfacing, slowly but surely, about the risks associated with this drug, and more recently attention has been brought to the true effects it may have on the developing brain.
Babies born to mothers who took Acetaminophen “long-term” (or, more than 29 times) during their pregnancy were found to have a 220% increased risk in being diagnosed with ADHD[26]. People immediately became skeptical when the findings first surfaced, but other studies have also reached the same conclusion: than an association does exist between gestational acetaminophen exposure and ADHD-like behaviors, use of ADHD medication, and ADHD diagnoses[27, 28, 29].
End
There are times when these meds might be fundamental, yet so as to assume a functioning job in our wellbeing, so as to settle on an educated choice, all the data must be laid before you. Furthermore, in my involvement with least, experts will in general illustrate the medicine, and symptoms regularly aren't examined until the point when the patient is encountering them. The information that a few drugs cause possibly irreversible harm to the cerebrum can represent the deciding moment a choice. Basic drugs, similar to Tylenol, frequently touted as incredibly safe stay routinely the motivation behind why somebody overdoses – in light of the fact that their threat simply isn't valued.